Table 2.

Multivariable analysis for progression-free survival

Multivariable
Factors	Category	Multivariable analysis (including all variables)
		HR (95% CI)	p-value
Sex	Female (vs. Male)	0.70 (0.29–1.72)	0.44
Age (Years)	≥40 (vs. < 40)	1.47 (0.47–4.58)	0.50
Performance Status	1 (vs. 0)	1.41 (0.56–3.59)	0.47
Histological subtype	Leiomyosarcoma (vs. UPS)	0.61 (0.17–2.18)	0.44
	Synovial sarcoma (vs. UPS)	0.48 (0.13–1.80)	0.28
	Others (vs. UPS)	0.65 (0.22–1.87)	0.42
Histological grade (FNCLCC)	Grade 3 (vs. 2)	0.56 (0.17–1.87)	0.34
Histological grade (Ki-67)	Grade 3 (vs. 2)	1.72 (0.51–5.80)	0.39
Tumor size	> 10 cm (vs. < 10 cm)	2.85 (1.18–6.92)	0.0203
Factors	Category	Multivariable analysis (backward elimination with alpha = 20%)
		HR (95% CI)	p-value
Sex	Female (vs. Male)
Age (Years)	≥40 (vs. < 40)
Performance Status	1 (vs. 0)
Histological subtype	Leiomyosarcoma (vs. UPS)
	Synovial sarcoma (vs. UPS)
	Others (vs. UPS)
Histological grade (FNCLCC)	Grade 3 (vs. 2)	0.42 (0.13–1.34)	0.14
Histological grade (Ki-67)	Grade 3 (vs. 2)	2.39 (0.75–7.62)	0.14
Tumor size	> 10 cm (vs. < 10 cm)	3.27 (1.41–7.59)	0.0057

Abbreviations: HR hazard ratio, CI confidence interval, UPS undifferentiated pleomorphic sarcoma, FNCLCC French Federation of Cancer Center