Table 1.

Input Parameters

Parameter	Base Case Value	Range	Reference
Variable Input parameters
Transition Probabilities
Healthy to Stroke	Calculated by age and sex	–	[12]
Healthy to MI	Calculated by age and sex	–	[12]
Healthy to CHF	Calculated by age and sex	–	[13]
Healthy to Death	Varies by age and sex	–	[15]
Invariable Input parameters
Transition Probabilities
Acute MI to Death	0.071328306	0.057–0.086	[16]
Acute MI to Post-MI	0.928671694	–	Calculated
Post-MI to CHF	0.021759765	0.017–0.026	[16]
Post-MI to Death	0.028583536	0.023–0.034	[16]
Remain in Post-MI	0.9496567	–	Calculated
Stroke to Death	0.069	0.055–0.083	[17]
Stroke to Post-Stroke	0.931	–	Calculated
Post-Stroke to Death	0.236	0.189–0.283	[17]
Remain in Post-Stroke	0.236	–	Calculated
CHF to Death	0.43	0.344–0.516	[18]
Remain in CHF	0.57	–	Calculated
Costs ($)a
Program Costs	127	102–152	Calculated
Stroke (once)	33,216	26,573-39,859	[19]
Post-Stroke (annually)	32,550	26,040-39,060	[20]
MI (once)	63,791	51,032–76-549	[21]
Post-MI (annually)	4106	3285-4927	[22]
CHF (annually)	13,619	10,895 − 16,342	[23]
Death	15,020	12,016-15,020	[21]
Utilities
Stroke	0.64	0.512–0.768	[24]
Post-Stroke	0.66	0.528–0.792	[24]
MI	0.7	0.56–0.84	[25]
Post-MI	0.88	0.704–0.95	[26]
CHF	0.71	0.568–0.852	[27]

Costs represented in 2015 U.S. Dollars