Table 1.
Comparisons of different groups in terms of renal function before and after treatments
| BUN before treatment (mg/dL) | BUN after treatment (mg/dL) |
Cr before treatment (mg/dL) |
Cr after treatment (mg/dL) |
Body weight (g) | SBP (mmHg) | DBP (mmHg) | |
|---|---|---|---|---|---|---|---|
| Control | 15.83 ± 1.6 | 15.33 ± 3.88 | 0.73 ± 0.05 | 0.7 ± 0.18 | 588.83 ± 44.74 | 125.50 ± 5.58 | 73.33 ± 4.18 |
| CKD | 35.15 ± 4.18# | 45.83 ± 4.96*,$ | 0.82 ± 0.20 | 1.7 ± 0.43*,$ | 551.67 ± 25.10 | 164.83 ± 7.31$ | 86.33 ± 4.5$ |
| CKD + ALT-711 | 32.5 ± 7.48# | 46 ± 17.32*,$ | 0.90 ± 0.22 | 1.82 ± 0.76$ | 585.67 ± 48.30 | 161.83 ± 5.95$ | 83.50 ± 4.72$ |
| CKD + SPL | 37.5 ± 8.17# | 43.83 ± 18.09$ | 1.08 ± 0.33 | 1.32 ± 0.33$ | 562.50 ± 54.24 | 165.17 ± 6.18$ | 85.00 ± 3.58$ |
BUN blood urea nitrogen, Cr creatinine, CKD chronic kidney disease, SPL spironolactone, SBP systolic blood pressure, DBP diastolic blood pressure, * Before treatment versus. After treatment, p < 0.05; # any groups compared with the control group before treatment, p < 0.05, $ any groups compared with the control group after treatment, p < 0.05