Fig. 10.

The role of PTX3-complement complexes in Bt phagocytosis by human monocytes. Pre-infection complexes between 10 μg/mL (a) or 30 μg/mL (b) of PTX3 and 10⁷ Bt were used to infect 1 × 10⁶ human monocytes in the presence of active complement (pooled NHS). Intracellular bacterial CFUs representative of phagocytosis were enumerated following 30 min of infection. An unpaired t-test did not reveal significant differences between phagocytosis for PTX3-pre-bound or unbound Bt. Data in (a) and (b) are each representative of n = 3 independent assays