Fig. 3.

Differential expression of immune response-related canonical pathways during infection of human monocytes with Bm or Bt. Among significantly enriched immune response-related pathways (p < 0.05), several pathways are significantly upregulated or downregulated during Bm or Bt infection of human monocytes at individual or all time points (1, 3, 6 h). Highlighted in bold are pathways that differ between Bm or Bt infections across two time points. Bm1/U1, Bm-infected human monocytes relative to uninfected monocytes incubated for 1 h; Bm3/U6, Bm-infected human monocytes for 3 h relative to uninfected monocytes incubated for 6 h; Bm6/U6, Bm-infected human monocytes relative to uninfected monocytes incubated for 6 h; Bt1/U1, Bt-infected human monocytes relative to uninfected monocytes incubated for 1 h; Bt3/U6, Bt-infected human monocytes for 3 h relative to uninfected monocytes incubated for 6 h; Bt6/U6, Bt-infected human monocytes relative to uninfected monocytes incubated for 6 h