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. 2019 Sep 6;52:49. doi: 10.1186/s40659-019-0255-2

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© The Author(s) 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 2 — Effects of astilbin on NRF2 activation. a The nuclear and cytoplasmic protein expression of NRF2 were determined using Western blot analysis. b The expression of HO-1 was determined using Western blot analysis. c mRNA levels of AKR1C1, GCLM and GCLC were evaluated using qPCR analysis. *P < 0.05 vs NC group