Table 1.
Characteristic of SWDs in mutant mice
|
Mutant mice |
Frequency (Hz) |
Mean duration (sec) |
Number of incidents per hour |
|---|---|---|---|
| α1A-/- | |||
| α1G+/+ | 3-4 | 2.0 ± 0.2 (0.7-5) | 161.7 ± 40.5 |
| α1G+/- | 3-4 | 2.1 ± 0.2 (0.7-5) | 156.2 ± 22.0 |
| α1G-/- | — | — | 0** |
| α1Atg/tg | |||
| α1G+/+ | 6-7 | 2.2 ± 0.2 (0.7-6) | 98.3 ± 12.2 |
| α1G+/- | 6-7 | 2.1 ± 0.2 (0.7-5) | 90.2 ± 15.3 |
| α1G-/- | — | — | 0** |
| β4lh/lh | |||
| α1G+/+ | 5-6 | 1.5 ± 0.1 (0.7-5) | 164.6 ± 25.7 |
| α1G+/- | 5-6 | 1.3 ± 0.1 (0.7-5) | 204.8 ± 26.0 |
| α1G-/- | 5-6 | 1.6 ± 0.2 (0.7-5) | 7.1 ± 4.7** |
| γ2stg/stg | |||
| α1G+/+ | 5-7 | 1.9 ± 0.2 (0.7-10) | 132.0 ± 8.7 |
| α1G+/- | 5-7 | 1.8 ± 0.2 (0.7-10) | 135.6 ± 20.0 |
| α1G-/-
|
5-7 |
1.3 ± 0.1 (0.7-2)* |
9.4 ± 3.4** |
Values, except for frequency, are means ± SEM. Values in parentheses are ranges. —, Not found. *p <0.05, **p <0.005 (mutants compared with α1G+/+ within each subgroup; two-tailed t test).