Skip to main content
. 2004 Jun 30;24(26):5974–5981. doi: 10.1523/JNEUROSCI.0122-04.2004

Figure 3.

Figure 3.

Localization of PrP C in MBP-PrP mice. A-C, Cellular distribution of PrP C with in the white matter of adult mice revealed by immunoelectron microscopy of gold-labeled anti-PrP antibody. Arrows indicate the location of the black gold particles. MBP-PrP mice display abundant decoration of myelin with gold particles. Scale bar, 5 nm. D-F, Immunofluorescence of primary optic nerve oligodendrocytes cultured from 7- to 8-d-old mice. Top row, expression of PrP is detectable only in transgenic oligodendrocytes (F), whereas the early oligodendrocyte marker MAG is expressed on all oligodendrocytes (bottom row). Scale bar, 5 μm.