Figure 10.
Unilateral variation of ḡh in the mathematical model of a heart interneuron half-center oscillator. A, Typical activity for an unbalanced half-center oscillator: membrane potential and h-current conductance (gh) for both the varied (mHNv) and the canonical (unvaried; mHNc) model heart interneuron. B, Increasing ḡh causes a decrease in burst duration of the unvaried canonical “neuron,” which is equivalent to the duration of the inactive phase of the varied neuron. Varied neuron burst duration remains constant. Inset, Results for symmetric variation of ḡh plotted with the same axes values. C, Final spike frequency of unvaried canonical neuron increases with increasing ḡh. Final spike frequency of varied neuron remains relatively constant. Inset, Results for symmetric variation of ḡh plotted with the same axes values. The error bars indicate the SD over n ≥ 25 cycles for the individual modeling trial.