Table 2.

Urinary bladder and body weights of 5-HT_3A wild-type and mutant mice

Age	Sex	5-HT3A	Bladder weight (gm)	Body weight (gm)	Bladder/body weight	Fold changed
6 weeks	Male	+/+	0.03 ± 0.0	25.65 ± 0.91	1.16 × 10−3
	Male	vs/vs	0.04 ± 0.0	24.61 ± 1.12	1.62 × 10−3	1.4
	Female	+/+	0.02 ± 0.0	17.60 ± 0.23	1.21 × 10−3
	Female	vs/vs	0.05 ± 0.0a	19.51 ± 1.02	2.41 × 10−3a	2.0
8 weeks	Male	+/+	0.03 ± 0.0	25.66 ± 0.98	1.33 × 10−3
	Male	vs/vs	0.09 ± 0.0b	26.07 ± 1.07	3.74 × 10−3c	2.8
	Female	+/+	0.03 ± 0.0	21.03 ± 0.45	1.27 × 10−3
	Female	vs/vs	0.07 ± 0.0a	21.44 ± 1.30	3.46 × 10−3a	2.7

^a p < 0.05.

^b p = 0.056.

^c p = 0.062; unpaired t test comparing 5-HT_3A^+/+ and 5-HT_3A^vs/vs mice.

^d Fold change in bladder/body weight ratios between 5-HT_3A^+/+ and 5-HT_3A^vs/vs mice.