Table 1.

Intrinsic and spontaneous membrane potential properties of mouse cortical neurons recorded in vivo

	Tg−			Tg+
Measurement	8-10 months	≥14 months	8-10 months	≥14 months
Down state
Membrane potential (mV)	−63.2 ± 4.6 (n = 8)	−61.8 ± 4.2 (n = 10)	−62.4 ± 3.8 (n = 8)	−63.5 ± 4.8 (n = 11)
Duration (msec)	652.4 ± 237.6 (n = 8)	769.0 ± 236.3 (n = 10)	721.7 ± 311.4 (n = 8)	684.8 ± 276.2 (n = 11)
Up state
Membrane potential (mV)	−52.8 ± 6.2 (n = 8)	−51.5 ± 4.9 (n = 8)	−53.1 ± 5.7 (n = 8)	−54.1 ± 5.2 (n = 8)
Duration (msec)	424.0 ± 280.5 (n = 8)	467.4 ± 322.1 (n = 10)	390.8 ± 316.2 (n = 8)	406.9 ± 388.5 (n = 11)
Spontaneous firing rate (Hz)	14.0 ± 6.7 (n = 8)	12.8 ± 6.0 (n = 10)	11.6 ± 8.5 (n = 8)	16 ± 9.3 (n = 11)