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. 2004 Apr 21;24(16):4011–4019. doi: 10.1523/JNEUROSCI.0178-04.2004

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Copyright © 2004 Society for Neuroscience 0270-6474/04/244011-09.00/0

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Figure 3. — Effect of synaptic state on P-S LTP. A, Changes in synaptic transmission after DP nerve tetanization depended on the initial EPSP amplitude. Small-amplitude synapses (filled circles) potentiated, whereas large-amplitude synapses (filled squares) became depressed. The one synapse of intermediate amplitude (filled triangle) that was tested exhibited little change. Inset, The mean ± SE percentage change in EPSP amplitude after tetanization was significantly different between the small- and large-amplitude synapses. B, Large-amplitude synapses exhibited less PPF during the pretest stage than small-amplitude synapses. Inset, In large-amplitude synapses (unfilled bars), the mean ± SE PPF ratio increased after DP nerve tetanization, but PPF was unchanged in small-amplitude synapses (filled bars).