Table 1.
Number of NK1R neuronal profiles and Nav 1.3 neuronal profiles per section in superficial laminas of dorsal horn at L3-L5
|
Group |
Contralateral to CCI |
|
|
Ipsilateral to CCI |
|
|
|
|---|---|---|---|---|---|---|---|
|
|
NK1R (a) |
Nav 1.3 (b) |
Merge b/a × 100% |
NK1R (c) |
Nav 1.3 (d) |
Merge d/c × 100% |
|
| Sham | 15.14 ± 3.22 | 1.13 ± 1.09 | 7.46 ± 1.36% | 20.29 ± 4.72 | 2.50 ± 1.41 | 19.90 ± 10.37% | |
| CCI | 17.86 ± 4.12 | 1.22 ± 1.15 | 6.83 ± 1.07% | 33.38 ± 5.15 | 22.00 ± 3.74 | 66.48 ± 10.68% | (-49.23%) |
| CCI plus Nav 1.3 MM | 14.28 ± 5.94 | 0.99 ± 1.03 | 6.93 ± 1.49% | 30.89 ± 5.80 | 24.59 ± 3.05 | 81.63 ± 16.76% | (-49.23%) |
| CCI plus Nav 1.3 AS |
15.43 ± 2.64 |
1.06 ± 0.94 |
6.87 ± 2.54% |
25.57 ± 5.46 |
8.07 ± 2.99*
|
33.63 ± 13.57%*
|
(-49.23%) |
Data represent mean ± SD values (n = 4 sections/6 animals/group).
*
p < 0.05, significant difference between the CCI and CCI plus 1.3 AS groups.