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Memory reactivation during a probe trial is necessary for the disruption of the reactivated memory by anisomycin. A, Experimental design. B, Probe trial 48 hr after the last training (saline, n = 10; ANI, n = 10). Mice were given injections of anisomycin or saline 24.5 hr before the probe trial. Time (seconds) spent in target (T), adjacent left (L), adjacent right (R), and opposite (O) quadrants during the probe trial (60 sec) is shown.
