Table 1.

B_max values of GR and MR cytosolic binding sites specifically labeled by [³H]corticosterone in the hippocampus and the cerebral cortex of GR-i mice compared with WT mice

	[3H]Corticosterone specifically bound, Bmax (fmol/mg protein)
	GR			MR
	WT (n = 3)	GR-I (n = 4)	WT (n = 3)	GR-I (n = 4)
Hippocampus	29.4 ± 3.5	14.4 ± 2.7*(-51%)	11.0 ± 1.4	12.0 ± 3.6(ns)
Cerebral cortex	11.8 ± 1.7	6.0 ± 1.3*(-49%)	4.5 ± 1.4	6.3 ± 2.3(ns)

B_max is expressed as femtomoles [³H]corticosterone specifically bound per milligram of protein. Each value is the mean ± SEM of n independent determinations. ns, Nonsignificant; *p<0.05, compared with respective values in WT mice (unpaired Student's t test).