Figure 8.

Effect of NOS inhibition on the expression of nestin and βIII-tubulin (β-tub) by proliferating cells. A, B, Percentage (A) and density (B) of recently divided cells characterized as nestin⁺/βIII-tubulin^-, nestin⁺/βIII-tubulin⁺, or nestin^-/βIII-tubulin⁺ in the SVZ (left) and OB (right). Mice were treated for 15 d with 90 mg/kg of L-NAME per day (filled bars) or with vehicle (open bars) and then injected with BrdU as described in Figure 3. For each group of mice, a total of 1165 BrdU⁺ cells was analyzed in the SVZ and 714 in the OB. Data are expressed as means ± SEM (n = 3; ^*p < 0.05).