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. 2004 Jan 7;24(1):85–95. doi: 10.1523/JNEUROSCI.1574-03.2004

Table 2.

Density of apoptotic cells in control and L-NAME-treated mice



Subventricular zone

Rostral migratory stream

Olfactory bulb
Treatment duration (d)
Saline
L-NAME
Saline
L-NAME
Saline
L-NAME
1 136 ± 18 102 ± 4 610 ± 111 505 ± 105 30 ± 4 27 ± 3
7 141 ± 8 142 ± 5 559 ± 42 551 ± 95 36 ± 2 31 ± 2
15
162 ± 2
161 ± 2
715 ± 64
673 ± 59
29 ± 2
31 ± 2

Mice received daily intraperitoneal injections of L-NAME (90 mg/kg) for the indicated time periods, and their brain sections were used for detection of apoptotic cells by the TUNEL technique 24 hr after the last injection. Data are expressed as number of cells/mm3 and presented as means ± SEM. Three animals were used for each condition.