Figure 4.

A, Righting reflex score assessing the ability of the pups to right themselves after being placed supine in control (abscissa C) and after sustained hypoxia for 30 min at E22 (H30 E22), 37-40 min at E22 d (H ≥ 37 E22), or at E21 (H ≥ 37 E21). Similarly, B shows the ability to suck and swallow. C shows the ability to reflexively turn the head away in response to introduction of a feeding dropper into the mouth. Data are shown as a box and whisker plot. Black circles, Mean; white circles, 99th percentile. Groups are significantly different by Kruskal-Wallis test. ^*p < 0.0224; Wilcoxon signed rank test compared with controls.