Figure 2.

DHPG and PGE₂ increase the frequency of the slow transient currents recorded in pyramidal neurons. A, Effect of bath applications of DHPG (10 μm; left) and PGE₂ (5-20 μm; right) on the frequency of the slow transient currents in neurons held at -80 mV (ANOVA test; p < 0.05). Numbers in parenthesis above the bars of the left histogram refer to the number of tested pyramidal neurons. B, Comparison of the cumulative frequency distributions of the amplitude (left) and of the 10-90% rise time (right) of the STCs recorded before (Ctrl) and during the application of DHPG (10 μm) for nine neurons showing both spontaneous and agonist-evoked STCs (Kolmogorov-Smirnov tests; p > 0.05). Ctrl, Control.