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. 2004 Sep 1;24(35):7604–7613. doi: 10.1523/JNEUROSCI.5328-03.2004

Figure 1.

Figure 1.

A-H, Transversal sections of the spinal cord (A, B), brainstem (C, D), and hypothalamus (E-H) stained for the transneuronal tracer (PRV). A, C, E, and G are sections from HSx rats, andB, D, F, and H are sections from HPx rats. A, B, Sections of the spinal cord at the thoracic level. The surviving time after PRV injection in the liver is 4 d. HSx rats do not show first-order labeling in the IML of the thoracic part of the spinal cord (A), where as first-order PRV labeling is observed in the thoracic part of the IML of the HPx rats (B). C, D, Sections at the level of the brainstem. The survival time after PRV injection in the liver is 5 d (C) or 6 d (D). PRV labeling is observed in the DMV of HSx rats (C) but not in the DMV of HPx rats (D). E-H, Sections at the level of the hypothalamus. The survival time is 6 d. Intense PRV labeling is observed in the PVN of both HSx rats (E) and HPx rats (F). PRV-labeled neurons are clearly observed in the SCN of HSx rats (G) and HPx rats (H).