Changes in plasma glucose concentrations during the 2 hr administration of TTX in the PVN, SCN, VMH, or DMH. Only inhibition of neuronal activity in the DMH and SCN induced a significant change (i.e., increase) in plasma glucose concentrations, respectively (p = 0.030 and p = 0.015 for the drug × sampling interaction). For basal concentrations (t = 0) and additional statistical details, see supplemental Tables 3 and 4 (available at www.jneurosci.org as supplemental material). Closed symbols indicate the effect of TTX administration, whereas open symbols show the result of the control experiment. *p < 0.1 and **p < 0.05 according to paired Student's t tests.