Table 1.

Neuronal survival after glutamate intoxication in mice given injections of dopamine or its type 1 receptor agonist and antagonist

	Treatment
Mice	Dopamine	SKF-38393	SCH-23390
Wild type	18 ± 2.5***	19 ± 3.2**	−11 ± 1.5**
SCID	NT	3 ± 1.8 (ns)	NT

Immediately after glutamate intoxication, mice were given systemic injections of the indicated drugs. Neuronal survival was determined 10 d later (see Materials and Methods). The results are expressed by changes (in percentage) in neuronal survival in treated mice relative to untreated mice. Each value represents a mean ± SEM of a group of at least five animals, and each experiment was performed at least twice, independently. Asterisks (^***p < 0.001; ^**p < 0.01) indicate statistical significance of the presented data from a single experiment using a Student's t test statistical analysis. NT, Not tested; ns, no statistical significance.