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. 2004 Jul 7;24(27):6144–6151. doi: 10.1523/JNEUROSCI.1090-04.2004

Figure 3.

Figure 3.

Mouse IgG immunohistochemistry showing antibody binding to Congophilic plaques in anti-Aβ antibody-treated mice but not control antibody-treated mice. A-D, Anti-mouse IgG-HRP immunohistochemistry counter stained with Congored to detect compact amyloid deposits. A, Representative amyloid deposit and associated anti-mouse IgG immunostaining (black) in the hippocampus of a mouse injected with the control antibody for 3 months. B-D, Representative amyloid deposit (red) associated with anti-mouse IgG immunostaining (black) in the hippocampus of a mouse injected with the anti-Aβ antibody for 1 month (B), 2 months (C), or 3 months (D). Magnification, 200×. Scale bar, 25 μm.