Chronic Ucn priming reduces the expression of spontaneous inhibitory synaptic potentials. A, Typical spontaneous PSPs observed in BLA projection neurons recorded from sham-primed control animals (top trace), acute Ucn-treated animals (middle trace), and Ucn-primed animals (bottom trace). Note the absence of spontaneous inhibitory synaptic potentials (downward deflections) in the trace from the chronic Ucn-primed animals. B, Bar histograms showing the percentage of cells that expressed both spontaneous EPSPs and IPSPs versus the percentage of cells that expressed only spontaneous EPSPs in each test group (chronic vehicle, n = 66; acute Ucn, n = 11; chronic Ucn, n = 51; Bic, n = 21). C, A significant increase in the amplitude of the spontaneous EPSPs was observed in the group of rats chronically treated with Ucn.