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Mice with hippocampal lesions and GluR-A-/- mice are impaired on a discrete trial, rewarded alternation (spatial nonmatching to place) task on the elevated T-maze (no floor inserts present). Mean percentage of correct responses ± SEM of 20 trials for experiment 1 (left) and experiment 3 (center), sham-operated controls (white bar) and mice with cytotoxic hippocampal lesions (black bar), and experiment 4 (right), wild-type controls (white bar) and GluR-A-/- mice (gray bar).
