Figure 1.

Adult XY aneuploidy is elevated in the Atm^-/- cerebral cortex but diminished in the Xrcc5^-/- and Trp53^-/- cerebral cortex. A mosaic display (Friendly, 1994) compares the proportion of cells with specific patterns of adult XY neural aneuploidy (OY, XXY, XYY, XO) in WT (top box) and mutant mice (genotypes indicated). For each category, the total number of nuclei analyzed (n) is indicated in parentheses. The width of each segment indicates the relative proportion of nuclei in each category (numerically represented in Table 1). Black bars (representing euploid nuclei) are broken to indicate that the relative widths are truncated. Colored bars (pink and blue) indicate aneuploid nuclei. Dark pink indicates X chromosome loss (OY), and X chromosome gain is indicated by light pink (XXY). Light blue indicates Y chromosome gain (XYY), and dark blue indicates Y chromosome loss (XO).