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A, B, Striatal DA, DOPAC, and HVA levels in wild-type mice injected with MPTP (30 mg/kg, i.p., single injection) and MPEP, SIB1893, or CPCCOEt (all at 10 mg/kg, i.p., administered 30 min before MPTP) (A), or MPTP (10 mg/kg, i.p., injected 4 times with a 2 hr interval) and MPEP (5 mg/kg, i.p., injected 4 times, 30 min before each MPTP injection) (B). Values are mean ± SEM of 6–10 determinations. *p < 0.05 (one-way ANOVA plus Fisher's PLSD) versus mice treated with MPTP and saline.
