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. 2004 Jul 21;24(29):6600–6610. doi: 10.1523/JNEUROSCI.1924-04.2004

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Copyright © 2004 Society for Neuroscience 0270-6474/04/246600-11.00/0

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Figure 8. — Effects of pretraining lesions (A, B) and post-training Mus plus Bac-induced inactivation (C) of the mOFC on cocaine-induced reinstatement (Cocaine REIN) of extinguished (EXT) cocaine-seeking behavior. Asterisks represent a significant difference relative to responding on the preceding extinction day and relative to the inactive lever (A, Tukey test, p < 0.05; C, ANOVA simple main effect test, p < 0.05). Daggers represent a significant difference in responding relative to the sham control group (Tukey test; p < 0.05). Sample sizes: mOFC lesion, n = 8; mOFC sham, n = 7; mOFC inactivation, n = 9.