Figure 2.

Time course for the stimulating effect of ethanol (EtOH) on 3α,5α-THP formation inisolated rat hippocampal tissue. Fresh hippocampal minces were incubated in the presence of ethanol (25, 50, and 100 mm) or vehicle at 34°C for various times (0-30 min), as described in Materials and Methods. Data are expressed as percentage change in 3α,5α-THP concentration from control value ± SEM obtained from hippocampal minces of eight rats per group of treatment or time point. ^*p < 0.05; ^**p < 0.01 versus control.