The body weight of 5-HT4 receptor-null and wild-type mice is similar during development. a, Data are mean ± SEM in body weight gain for a group of 20 wild-type and knock-out animals. Repeated measures ANOVA revealed no significant difference in body weight between mice of both genotypes from day 21 to 52 after birth. b-f, No significant difference between wild-type (n = 14) and 5-HT4 receptor-null (n = 13) mice has been found at 4 months of age in body weight (b), feeding (c), water intake (d), or metabolism (e,f).