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. 2004 Mar 31;24(13):3370–3378. doi: 10.1523/JNEUROSCI.1633-03.2004

Figure 4.

Figure 4.

Activation of mGluR5 but not the α7 nAChR is required for synthetic Aβ inhibition of LTP induction. A, LTP induction in the presence of 500 nm synthetic Aβ plus the group I–II antagonist LY341495 was not significantly reduced compared with controls. B, LTP induction in the presence of 500 nm synthetic Aβ plus the mGluR5 antagonist MPEP was not significantly reduced compared with controls. C, LTP induction in the presence of the α7 nAChR antagonist MLA and 500 nm Aβ was significantly reduced compared with controls. Traces a–c illustrate EPSPs before HFS and 20 min and 60 min after HFS, respectively.