Figure 2.

Representative traces for Q_T and ΔF₃₈₀ at transmitter-gated channels. For all panels in this figure, the black traces are transmitter-evoked currents (in amperes) and the integral of the current Q_T (in nanocoulombs), whereas the gray traces are the ΔF₃₈₀ (in bead units). Appropriate agonists were applied for the times indicated by the solid bars above the traces. These agonists were as follows: 100 μm glutamate in 0 mm extracellular Mg²⁺ with 100 μm glycine for NR1/NR2A, 100 μm (–)-nicotine for α4β2, 10 μm serotonin for 5-HT_3A, and pH 5.5 for VR1.