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. 2004 Oct 20;24(42):9405–9413. doi: 10.1523/JNEUROSCI.0899-04.2004

Figure 1.

Figure 1.

NT-3 overexpression does not alter baseline mechanical sensitivity of the hindpaw. Mechanical responsiveness of high-OE myo/NT-3, low-OE myo/NT-3, and wild-type mice was assessed using a series of nine different von Frey monofilaments. Data are plotted as percentage withdrawal responses from five applications to each foot (10 total for each monofilament). No significant differences were detected among the groups, revealing that the presence of the NT-3 transgene in low-OE myo/NT-3 mice or NT-3 overexpression in high-OE myo/NT-3 mice do not alter mechanical sensitivity of the paw (p > 0.05; ANOVA). Error bars represent SEM.