Table 1.
Cell cycle parameters for nestin/IGF-I transgenic and normal littermate control mice at E14
|
Cell cycle parameter |
Nestin/IGF-I transgenic (hr) |
Control (hr) |
|---|---|---|
| Time required to reach maximum LI | 10.81 | 12.66 |
| TC | 15.87 | 17.92 |
| TS | 5.06 | 5.26 |
| TG2+M | 2.0 | 2.0 |
| TM | 0.61 | 0.56 |
| TG2 | 1.39 | 1.45 |
| TG1
|
8.81 |
10.66 |
Mean lengths for cell cycle phases were measured using cumulative and single injection BrdU-labeling protocols. The maximum LI attained is equivalent to the GF, which represents the proportion of actively dividing cells in the ventricular zone.