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. 2004 Nov 10;24(45):10149–10158. doi: 10.1523/JNEUROSCI.3203-04.2004

Figure 8.

Figure 8.

Dopamine evokes morphological alterations via stimulation of endogenous glutamate release. The areas of the glial cell profiles in the IPL are given as percentage of control (100%). A, Effects of ATP (200 μm), GABA (1 mm), or dopamine (100 μm) at control conditions and during co-exposure with glutamate (1 mm). B, The AMPA-kainate receptor blocker CNQX (50 μm) inhibits the dopamine effect on glial cell morphology. C, Time dependence of the dopamine (100 μm) effect. In A and B, the effects were measured after a 10 min exposure. Means ± SEM of 3-10 experiments. Significant differences versus control: •p < 0.05; •••p < 0.001. Significant effect of dopamine during glutamate exposure: ○p < 0.05.