Figure 7.

Indirect IHC analysis of photoreceptor differentiation during postmetamorphic retinal growth and regeneration. The identity of the screened primary antibodies (zpr-1, zpr-3, or combined zpr-1 and anti-rhodopsin) is indicated to the left of each row, and the retinal assembly condition (growth from the CGZ or regeneration from the edge of a lesion site) is indicated along the top of each column. The green and red arrows indicate the estimated distance from the CGZ or lesion site to the nearest cone or rod photoreceptor, respectively. Note that in both conditions of retinal assembly, the length of the red arrows always exceeds that of the corresponding green arrows (see Fig. 2; quantification is presented in Fig. 10), consistent with a cone-to-rod sequence of photoreceptor differentiation (see Results).