Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2004 Feb 25;24(8):1888–1896. doi: 10.1523/JNEUROSCI.3809-03.2004

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2004 Society for Neuroscience 0270-6474/04/241888-09.00/0

PMC Copyright notice

Figure 5. — Lysosomal inhibitors stabilize α-syn aggregates in differentiated SH-SY5Y cells. A, Differentiated SH-SY5Y cells overexpressing α-syn were treated with Baf, cathepsin inhibitor I, or 3-MA for 24 hr at the indicated concentrations. Triton-soluble (TX-s) and Triton-insoluble (TX-p) fractions were obtained from cell extracts and analyzed by Western blotting. B, Progressive accumulation of aggregates in differentiated SH-SY5Y after treatment with 20 nm Baf. C, Baf treatment does not lead to aggregate accumulation in undifferentiated SH-SY5Y cells.