FIGURE 5.

Deletion of one or both p75NTR alleles in gp120 mice does not affect locomotion or exploration in a novel environment. 8–10 month-old mice were exposed for 5 min to an open field. (A) Cumulative distance traveled in the open field. (B) Total time spent ambulating in the open field. (C) Percent of total beam breaks occurring in the center of the open field. ANOVA with Tukey’s HSD. ^∗p < 0.05 vs. WT. (D) Total active beam breaks (ambulatory and stereotypic movements) occurring within the 5-min trial. Data are expressed as mean ± SEM. n = number of animals per group.