Table 1. Clinical characteristics of participants in the different GFR categories.
| Normal | G1 | G2 | G3 | G4 | G5 | P value | |
|---|---|---|---|---|---|---|---|
| N | 47 | 20 | 26 | 19 | 11 | 9 | |
| age | 30.8 ±10.5 | 40.6 ±11.2 | 56.7 ±12.5 | 61.8 ±14.9 | 66.0 ±13.3 | 66.9 ±13.6 | < 0.01 |
| male,n (%) | 21 (44.7) | 10 (50.0) | 20 (76.9) | 15 (78.9) | 6 (54.5) | 6 (66.6) | 0.693 |
| height (cm) | 164.3 ±8.9 | 166.4 ±8.5 | 165.3 ±8.6 | 163.7 ±8.5 | 163.9 ±11.2 | 158.2 ±7.9 | 0.378 |
| weight (kg) | 58.7 ±11.6 | 69.3 ±15.6 | 61.9 ±11.7 | 67.6 ±14.9 | 62.7 ±13.9 | 55.8 ±9.5 | 0.032 |
| Body surface area (m2) | 1.634 ±0.19 | 1.767 ±0.21 | 1.501 ±0.54 | 1.594 ±0.50 | 1.677 ±0.23 | 1.556 ±0.14 | 0.217 |
| AST (U/L) | 18.0 ±6.2 | 23.2 ±12.7 | 22.9 ±8.6 | 24.2 ±8.0 | 19.1 ±6.0 | 21.4 ±7.6 | 0.420 |
| ALT (U/L) | 16.1 ±15.5 | 23.8 ±12.1 | 19.2 ±9.1 | 20.6 ±11.1 | 11.7 ±3.7 | 15.2 ±4.1 | 0.029 |
| creatinine (mg/dL) | 0.718 ±0.15 | 0.684 ±0.16 | 0.952 ±0.22 | 1.716 ±0.45 | 2.245 ±0.70 | 5.143 ±2.33 | < 0.01 |
| cystatine-C (mg/dL) | no data | 0.710 ±0.07 | 1.007 ±0.11 | 1.657 ±0.24 | 2.415 ±0.33 | 4.021 ±0.66 | < 0.01 |
| urea nitrogen (mg/dL) | 13.2 ±3.2 | 12.4 ±3.1 | 15.2 ±4.1 | 26.4 ±6.9 | 36.8 ±8.0 | 56.7 ±20.0 | < 0.01 |
| eGFR creat (ml/min/1.73m2) | 93.0 ±12.9 | 92.4 ±18.6 | 63.3 ±14.3 | 33.0 ±9.9 | 23.2 ±6.2 | 10.2 ±3.6 | < 0.01 |
| eGFR cys (ml/min/1.73m2) | no data | 114.2 ±14.8 | 73.7 ±7.2 | 40.1 ±7.4 | 23.9 ±3.7 | 11.3 ±3.3 | < 0.01 |
| white blood cell (*109/L) | 5.5 ±1.2 | 6.4 ±2.3 | 6.1 ±1.6 | 5.5 ±1.4 | 5.8 ±1.8 | 6.5 ±2.1 | 0.123 |
| hemoglobin (g/dL) | 13.6 ±1.5 | 14.4 ±1.6 | 13.8 ±1.5 | 13.1 ±1.6 | 11.7 ±1.3 | 10.8 ±1.4 | < 0.01 |
| hematocrit (%) | 41.0 ±4.0 | 42.6 ±4.1 | 40.7 ±4.0 | 38.4 ±4.6 | 35.6 ±3.5 | 33.1 ±3.4 | < 0.01 |
| platelets (*109/L) | 247.1 ±49.4 | 242.1 ±64.6 | 245.4 ±52.1 | 215.3 ±43.7 | 353.6 ±463.9 | 188.2 ±43.5 | 0.473 |
Data are presented as the mean ± standard deviation, as number (%).
GFR categories: Categorized according to the KDIGO 2012 by eGFRcys.
G1: eGFRcys ≥90 mL/min/1.73 m2; G2: eGFRcys = 60–90 mL/min/1.73 m2; G3: eGFRcys = 30–60 mL/min/1.73 m2; G4: eGFRcys = 15–30 mL/min/1.73 m2; G5: eGFRcys ≤15 mL/min/1.73 m2.
P value was calculated by one-way analysis of variance.