Table 2. Summary of amino acid and protein quantification from Lcn2+/+ and Lcn2-/- BALF.
| Metabolite* | Lcn2+/+ BALF (mean ± S.D.) | Lcn2-/- BALF (mean ± S.D.) | Fold change | P Value | Adjusted P Value |
|---|---|---|---|---|---|
| Total protein | 275 ± 100 | 457 ± 146 | 1.66 | 0.0513 | - |
| Total free amino acids | 276 ± 66.2 | 405 ± 93.6 | 1.47 | 0.0221 | - |
| Alanine | 31.4 ± 10.6 | 48.6 ± 11.9 | 1.55 | 0.0350 | 0.0186 |
| Alpha-aminoisobutyric acid | 0.22 ± 0.05 | 0.46 ± 0.06 | 2.03 | 0.0012 | 0.0019 |
| Asparagine | 6.54 ± 1.07 | 8.47 ± 2.09 | 1.29 | 0.0734 | 0.0346 |
| Aspartic acid | 11.7 ± 6.73 | 12.6 ± 4.53 | 1.08 | 0.2949 | 0.1123 |
| Cystine | 1.03 ± 0.45 | 0.34 ± 0.28 | 0.34 | 0.0082 | 0.0054 |
| Glutamate | 9.85 ± 3.86 | 16.7 ± 9.87 | 1.70 | 0.0350 | 0.0186 |
| Glutamine | 74.1 ± 25.2 | 95.3 ± 24.2 | 1.29 | 0.1807 | 0.0723 |
| Glycine | 43.4 ± 8.55 | 55.9 ± 12.9 | 1.29 | 0.0513 | 0.0256 |
| Histidine | 8.59 ± 2.37 | 10.3 ± 1.84 | 1.21 | 0.1375 | 0.0579 |
| Isoleucine | 5.89 ± 1.69 | 10.1 ± 1.98 | 1.73 | 0.0047 | 0.0037 |
| Leucine | 11.2 ± 3.01 | 19.7 ± 4.10 | 1.76 | 0.0023 | 0.0023 |
| Lysine | 19.3 ± 4.92 | 25.4 ± 8.81 | 1.31 | 0.1375 | 0.0579 |
| Methionine | 3.99 ± 1.19 | 9.64 ± 1.42 | 2.41 | 0.0012 | 0.0019 |
| Ornithine | 3.27 ± 1.18 | 6.77 ± 1.73 | 2.07 | 0.0047 | 0.0037 |
| Phenylalanine | 7.95 ± 1.19 | 13.0 ± 3.04 | 1.64 | 0.0023 | 0.0023 |
| Proline | 5.95 ± 1.37 | 11.8 ± 2.42 | 2.00 | 0.0012 | 0.0019 |
| Sarcosine | 0.23 ± 0.04 | 0.35 ± 0.08 | 1.51 | 0.0140 | 0.0086 |
| Threonine | 9.35 ± 2.07 | 17.6 ± 4.02 | 1.89 | 0.0012 | 0.0019 |
| Tyrosine | 4.78 ± 0.83 | 9.87 ± 2.01 | 2.06 | 0.0012 | 0.0019 |
| Tryptophan | 3.73 ± 1.48 | 6.92 ± 1.91 | 1.85 | 0.0082 | 0.0054 |
| Valine | 13.6 ± 4.20 | 25.4 ± 3.96 | 1.86 | 0.0023 | 0.0023 |
*Total protein concentration in μg/mL, all amino acid concentrations in μM