Table 1.
Characteristic | Value |
---|---|
Age, mean (SD), y | 65 (10) |
Weight, mean (SD), kg | 86 (20) |
Sex, male, no. (%) | 76 (54) |
Race/ethnicity, no. (%) | |
White | 133 (94) |
Black | 5 (4) |
Hispanic | 4 (3) |
Comorbidities, no. (%) | |
Coronary heart diseaseb | 40 (28) |
Hypertensionc | 70 (49) |
Diabetes mellitus type 2 | 25 (18) |
Statin,no. (%) | |
Simvastatind | 60 (42) |
Atorvastatin | 29 (20) |
Rosuvastatin | 23 (16) |
Pravastatin | 19 (13) |
Lovastatin | 6 (4) |
Red yeast rice | 4 (3) |
Pitavastatin | 1 (1) |
Normalized statin dose, mean (SD), mge | 17 (18) |
Normalized statin dose, mean (SD), mg/kg body weighte | 0.2 (0.2) |
Duration of statin therapy, mean (SD), y | 6.8 (5.7) |
Some percentages do not total to 100 because of rounding.
All patients with coronary heart disease had normal ejection fraction and normal left ventricular end-diastolic pressure before statin treatment.
Hypertension without evidence of left ventricular hypertrophy.
Includes patients receiving the ezetimibe/simvastatin combination drug (n=10).
Dose normalized to atorvastatin potency; excludes red yeast rice.
SD = standard deviation.