Table 1.
Clinical characteristics of renal medullary carcinoma cases (n=20).
| Case # | Age (yr) | Sex | Race | SCT | Presentations | Procedure | Side | Size (cm) | Stage at diagnosis | Metastatic site(s) | Systemic treatment | Outcome (f/u months) |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | 41 | M | Black | Y | Right abdominal pain | Nx | R | 5.6 | III | None | Chemoradiation | DOD (23) |
| 2 | 12 | M | Unknown | Y | Hematuria | Nx | R | 6.5 | IV | Vertebra and LNs | Chemotherapy | DOD (8) |
| 3 | 25 | F | Other | Y | Hematuria | Nx | R | 6.5 | III | RP and mediastinal LNs | Chemotherapy | AWD (27)* |
| 4 | 46 | M | Black | Y | Hematuria, back pain | Nx | R | 5.7 | I | None | Chemotherapy | DOD (3) |
| 5 | 7 | F | Black | Y | Abdominal pain, vomiting | Nx | L | 6 | IV | RPLN and soft tissue | Chemotherapy | DOD (24) |
| 6 | 23 | F | Black | Y | Right flank pain | Nx | R | 8.9 | III | Bones, lungs, pleura, pericardium, and breast | Chemotherapy | DOD (8) |
| 7 | 17 | M | Other | Y | Hematuria, flank pain | Nx | R | 5.5 | IV | RP LNs, lungs | Chemotherapy | AWD (13)* |
| 8 | 15 | F | Black | Y | Hematuria, flank pain | Nx | R | 9 | IV | Right lung, liver, RP LNs, pleura | Chemotherapy | AWD (7)* |
| 9 | 13 | M | Black | Y | Hematuria, flank pain | Nx | R | 4 | III | None | None | AWD (78)* |
| 10 | 20 | M | Black | Y | Flank pain, night fever | Renal bx | R | 5.3 | III | RP LNs, lungs, liver, pleura | Chemotherapy | DOD (10) |
| 11 | 22 | M | Other | Y | Flank pain, hematuria | Renal bx | R | 6.5 | IV | Liver, RP LNs, lungs | Chemotherapy | DOD (3) |
| 12 | 20 | M | Black | Y | Left flank pain | Pleural bx | L | 7 | IV | Lung, RP LNs | Chemotherapy | DOD (5) |
| 13 | 28 | F | Black | Y | Skin nodules | Chest wall bx | R | 5.9 | IV | LNs, skin, muscle, lungs, brain | Chemotherapy | DOD (11) |
| 14 | 39 | M | Black | Y | Weight loss, flank pain | LN bx | R | 6.8 | IV | Mesenteric, RP, and inguinal LNs, spleen, liver, bone | Chemotherapy | DOD (14) |
| 15 | 27 | F | White | Y | Left flank pain | RP bx | L | 7.6 | IV | Liver, LNs, spine, lung | Chemotherapy | DOD (4) |
| 16 | 25 | M | Black | Y | Incidental renal mass | Pleural bx | R | 4 | IV | Pleura and lung | Chemoradiation | DOD (8) |
| 17 | 28 | F | Black | Y | Cough, dyspnea | LN bx | R | 3.2 | IV | Axillary LNs and lung | Chemotherapy | DOD (11) |
| 18 | 10 | M | Black | Y | Cough, chest pain | LN bx | L | 2.7 | IV | Lungs, liver, LNs | Chemotherapy | DOD (10) |
| 19 | 61 | F | Black | Y | Hematuria | LN bx | L | 6.8 | III | RP LNs, liver, bone | Chemotherapy | AWD (8) |
| 20 | 34 | M | Black | Y | Short of breath | Pleural bx | L | n/a | IV | Pleura, RP LNs | None | DOD (1) |
SCT, sickle cell trait; Nx, nephrectomy; bx, biopsy; LN, lymph node; RP, retroperitoneal; AWD, alive with disease; DOD, dead of disease.
*
Patient subsequently lost to follow-up