. Author manuscript; available in PMC: 2020 Sep 30.

Published in final edited form as: Stat Med. 2019 Jul 8;38(22):4334–4347. doi: 10.1002/sim.8300

Table 4.

Results for analysis of dental data – inference for mediation (natural direct (D) and indirect (I)) estimands on mean ratio scale. Estimates and, for indirect effects, proportions are given along with bootstrap percentile method 95% confidence intervals (499 bootstrap samples generated, 489 used). Subscripts indicate time (age in months) for (cross-sectional) indirect effects. ABC (area between the curves) provides overall indirect effect for specified intervention (starting at indicated time)

Estimand	Est	95% CI	Prop.	95% CI
D^r	2.05	(1.02, 4.19)	-	-
$I_{8}^{r}$	0.98	(0.53, 1.61)	−0.03	(−4.35, 1.87)
$I_{18}^{r}$	0.91	(0.72, 1.76)	−0.14	(−0.88, 0.85)
$I_{36}^{r}$	1.31	(1.04, 2.11)	0.27	(0.03, 0.93)
ABC^r(A^1,0)	0.64	(−6.27, 16.39)	0.03	(−0.38, 0.89)
ABC^r(A^1,8)	0.01	(−4.40, 11.83)	0.0007	(−0.26, 0.56)
ABC^r(A^1,18)	−0.03	(−0.63, 1.58)	−0.002	(−0.03, 0.08)