Fig. 2.

Administrations of cord blood cells with plasma in the 6-OHDA PD rat model: Assessment of 6-OHDA induced neurological deficits (a). Neurological function was also assessed using the elevated body swing test at Day 14, 28, 42, and 56 post treatment. Animals receiving stem cells exhibited a significant reduction in swing bias observed on Days 28, 42, and 56. (*** p < 0.001). Administrations of cord blood cells with plasma in the 6-OHDA PD rat model: Assessment of motor function improvement (b). Motor coordination and balance were assessed post-treatment on Day 28, 42, and 56. Improvements in motor coordination were observed at 28 days with combined cord blood cell and plasma treatment, but not at the later time points (42 and 56 days). Administrations of cord blood cells with plasma in the 6-OHDA PD rat model: Assessment of locomotor improvements (c). Locomotor performance was assessed post-treatment on Day 28, 42, and 56. The combination of cord blood cells with plasma resulted in significant improvement in motor coordination at each time point tested (*** p < 0.001)