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Effect of 7-HC intraperitoneal treatment on formalin-induced chronic inflammation in rats.
| Group | Change in paw thickness | % Inhibition |
|---|---|---|
| Control (DMSO) | 1.25 ± 0.112 | 0% |
| Diclophenac (10 mg/kg) | 0.498 ± 0.067** | 60.2% |
| 7-HC (10 mg/kg) | 0.740 ± 0.051** | 40.9% |
| 7-HC (25 mg/kg) | 0.760 ± 0.123** | 39.3% |
| 7-HC (50 mg/kg) | 0.304 ± 0.075* | 75.7% |
| 7-HC (100 mg/kg) | 0.462 ± 0.121** | 63.1% |
*Significant difference (p < 0.05) with respect to the control.
