Table 1.
Body weight, liver body weight ratio, and serum biochemical parameters test results in control and MCDD rats treated with vehicle or CeO2NPs.
| Control (n = 5) | MCDD rats | ||
|---|---|---|---|
| Vehicle (n = 8) | CeO2NPs (n = 7) | ||
| Body weight (g) | 425.6 ± 6.7 | 275.3 ± 4.8*** | 274.5 ± 3.4*** |
| Liver/body weight (%) | 2.9 ± 0.18 | 4.1 ± 0.17** | 4.2 ± 0.17*** |
| Alanine transaminase (U/L) | 35.3 ± 3.1 | 179.1 ± 26.6** | 199.8 ± 24.2*** |
| Aspartate transaminase (U/L) | 49.1 ± 6.4 | 143.8 ± 14.52* | 149.1 ± 15.1** |
| Gamma Glutamyl Transpeptidase (U/L) | 2.1 ± 0.02 | 3.2 ± 0.5 | 2.8 ± 0.15 |
| Total cholesterol (mg/dL) | 69.4 ± 4.9 | 25.8 ± 1.7*** | 28.4 ± 2*** |
| Total bilirubin (mg/dL) | 0.00 ± 0.08 | 0.29 ± 0.06* | 0.24 ± 0.05 |
| Triglycerides (mg/dL) | 192.2 ± 14.8 | 20.2 ± 1.4*** | 22.7 ± 2.1*** |
| Glucose (mg/dL) | 145.1 ± 6.9 | 120.2 ± 6.9 | 126.6 ± 4.6 |
| Total proteins (g/L) | 65.8 ± 1.2 | 63.3 ± 1.4 | 63.1 ± 1.2 |
| Albumin (g/L) | 34.9 ± 0.5 | 37.1 ± 0.7 | 37.2 ± 0.64 |
*p < 0.05,**p < 0.01, ***p < 0.001 compared to control group. One-way ANOVA with Newman-Keuls post hoc test and Kruskal-Wallis with Dunn’s test post hoc when appropriate. Results are shown as mean ± SEM.