Fig. 6.

Genealogies of maternal and paternal cell lineages delineated by early embryonic and peri-PGC mutations. Parental embryonic lineages reconstructed for each pedigree in the two largest pedigrees (CBGP8 (a) /GPCB2(b)), as paternal (P) or maternal (M), with each lineage numbered. Mutations delineating the lineages are colour-coded according to their temporal strata as listed in Supplementary Data 1. WGS and genotyped offspring are shown as red and black numbered circles, respectively. Offspring are numbered and ordered according to litter; for example, in lineage P2, individuals 2, 3 and 7 belong to the same litter, whereas numbers 28 and 39 arose in separate, later litters. Lineages P5, M3, M8 and P10 represent offspring without shared mutations and may contain several uncharacterised lineages. Minimal lineages for the four smaller pedigrees can be found in Supplementary Fig. 5