. 2019 Sep 6;9:12830. doi: 10.1038/s41598-019-49073-5

Table 1.

Summary of the drug combinations of paclitaxel and trastuzumab administered.

Regimen	Paclitaxel Dosage	Trastuzumab Dosage	Timetable
Paclitaxel prior to trastuzumab	25 nM	25 μg/mL	Paclitaxel applied day 1 for 24 hours, trastuzumab applied day 2 for 24 hours
Paclitaxel prior to trastuzumab	100 nM	25 μg/mL
Trastuzumab prior to paclitaxel	25 nM	25 μg/mL	Trastuzumab applied day 1 for 24 hours, paclitaxel applied day 2 for 24 hours
Trastuzumab prior to paclitaxel	100 nM	25 μg/mL
Paclitaxel and trastuzumab applied simultaneoulsy	25 nM	25 μg/mL	Paclitaxel and trastuzumab applied day 1 for 24 hours
Paclitaxel and trastuzumab applied simultaneoulsy	100 nM	25 μg/mL	Paclitaxel and trastuzumab applied day 1 for 24 hours