Expression of SGK1, E-cadherin, N-cadherin and Vimentin following the treatment of high glucose, TGF-β1 or GSK in HK-2 cells. The expression of SGK1 was measured via (A) western blotting and (B) reverse transcription-quantitative PCR. (C) The expression of E-cadherin, N-cadherin and Vimentin was determined via western blotting. ***P < 0.001 vs. the control; #P < 0.05, ##P < 0.01 and ###P < 0.001 vs. the Glucose group; ΔΔP < 0.01 and ΔΔΔP < 0.001 vs. the Glucose+TGF-β1 group. SGK1, serum and glucocorticoid induced kinase; TGF-β1, transforming growth factor; GSK, GSK650394.