Table 4.
KEGG pathway enrichment analysis of BSG co-expressed genes
| KEGG ID | KEGG Term | Count (%) | P-Value | Genes symbol |
|---|---|---|---|---|
| hsa03010 | Ribosome | 23 (5.58) | 2.43E-15 | RPL18, RPL14, RPL35, RPLP2, RPL36, RPS5, RPL28, RPS3, RPL29, RPS19, etc |
| hsa00190 | Oxidative phosphorylation | 26 (6.31) | 2.52E-14 | ATP5D, UQCRC1, NDUFB7, ATP5G2, COX5A, COX5B, UQCRQ, ATP6V0B, NDUFS7, NDUFS5, etc |
| hsa05016 | Huntington’s disease | 29 (7.04) | 1.66E-13 | ATP5D, POLR2F, UQCRC1, CLTB, POLR2E, POLR2L, NDUFB7, AP2S1, POLR2I, ATP5G2, etc |
| hsa05012 | Parkinson’s disease | 22 (5.34) | 8.69E-11 | ATP5D, NDUFA2, NDUFA3, UQCRC1, NDUFB10, NDUFB7, NDUFA7, COX8A, COX4I1, ATP5G2, etc |
| hsa05010 | Alzheimer’s disease | 24 (5.83) | 2.40E-10 | ATP5D, NDUFA2, NDUFA3, UQCRC1, NDUFB10, NDUFB7, NDUFA7, COX8A, COX4I1, ATP5G2, etc |
| hsa04260 | Cardiac muscle contraction | 10 (2.43) | 4.48E-04 | UQCRC1, UQCR11, UQCRH, COX8A, COX6B1, COX4I1, COX6A1, COX5A, UQCRQ, COX5B |
| hsa00240 | Pyrimidine metabolism | 10 (2.43) | 0.00188043 | NME4, ITPA, NME2, POLR2F, POLR2E, NME3, POLR2L, POLD2, POLR2I, ZNRD1 |
| hsa03040 | Spliceosome | 11 (2.67) | 0.00398349 | DHX8, LSM7, PQBP1, SNRPB, SNRPA, LSM4, SF3B5, SF3A2, BUD31, NAA38, etc |
| hsa00230 | Purine metabolism | 12 (2.91) | 0.00546642 | NME4, ITPA, NME2, POLR2F, POLR2E, NME3, POLR2L, POLD2, POLR2I, ZNRD1, etc |
| hsa03020 | RNA polymerase | 5 (1.21) | 0.00877957 | POLR2F, POLR2E, POLR2L, POLR2I, ZNRD1 |
| hsa00051 | Fructose and mannose metabolism | 4 (0.97) | 0.0786479 | ALDOA, GMPPA, TSTA3, PHPT1 |
| hsa05110 | Vibrio cholerae infection | 5 (1.21) | 0.08368437 | SEC61B, ARF1, KDELR1, ATP6V0B, ATP6V1F |
| hsa03018 | RNA degradation | 5 (1.21) | 0.08802319 | EXOSC4, LSM7, LSM4, EXOSC1, NAA38 |